WORLD’S MOST VERSATILE AND COST-EFFICIENT Single cell collection and tissue microdissection systemsOur products VERSATILITY AND EFFICIENCY
Where it is used
There is a high demand for methods permitting simple and rapid collection of individual cells or tissue regions in the numerous fields of biomedical sciences from single cell analysis and stem cell research to neuroscience and cancer diagnostics. Existing approaches are costly, sophisticated and methodologically limited.
To address this problem, NeuroInDx developed a product line of versatile instruments (UnipicK™, UnipicK+™ and A-picK™) which are based on our patented vacuum pulse based cell and tissue acquisition technology. Rapid collection of single or multiple cells can be performed from virtually any cell culture and various tissues including FFPE specimens. Our products’s versatility, cost effectiveness, streamlined operation, and cost efficiency, make them a cell collection and tissue acquisition system of choice.
Applications include but are not limited to:
- Single Cell Analysis
- Rare Cell Isolation
- Collection of Circulating Tumor Cells (CTCs)
- Stem Cell Picking
- Single Cell Cloning
- Clonal Expansion
- Complex Tissue Microdissection
- Organoid Microdissection
- Acquisition of Regions of Interest (ROIs) from FFPE Specimen
- Single Cell Adhesion Assay
How it works
Single cell or tissue area collection and deposition may be performed manually (UnipicK™, UnipicK+™) or automatically (UnipicK+™, A-picK™). The procedure is simple, rapid, and requires minimal training.
All instruments are available as free-standing versions and directly integrated with Olympus inverted microscopes (IX53, IX71, IX81, IX73 and IX83). Free standing versions utilize a patented universal straddle (US D782,554) that accommodates a range of commercially available inverted microscopes. The instruments demonstrate high consistency and accuracy of both dispensing and acquisition with no effect on cell viability.
The working concept is to collect cells and tissue regions under direct microscopic visualization by applying precise vacuum pulses into a specifically designed disposable capillary unit.
News and events
Investigators from Kyoto University, Japan used UnipicK+ to measure detachment strength of HUVEC cells in response of sodium selenite concentrations. Results have important implications for in vitro construction of microvasculature.
Investigators from City University of Hong Kong used NDX instrument for the collection of individual cells from non-small lung cancer fingers for the follow-up mechanical and gene expression analysis. The study published in iScience identified genes responsible for cancer finger formation and migration.
Labeled dental primary afferent neurons were collected for RNA sequencing using UnipicK in a study uncovering mechanisms of the dental cold sensing system performed by investigators from Friedrich Alexander University of Erlangen-Nuremberg, Germany and Harvard Medical School, USA. The study was published in Science Advances.
Application of A-picK for the concurrent analysis of single cell detachment/adhesion force was published in SLAS Technology journal
UnipicK+ was used for single-cell transcriptomics study of olfactory sensory neurons to unravel mechanisms of odor encoding. The results were published in Current Biology by Firmenich investigators.
NDX technology was used in a study of Circulating Tumor Cells in Early-Stage Non-Small Cell Lung Cancer.
NeuroInDx’s instruments are installed around the world in over hundred academic and industrial locations. We take care of our customers and provide ongoing support from the initial installation and training to protocol optimization and troubleshooting.
- Free on-site installation
- Free on-site training
- Worldwide shipping and delivery
- Life-time free technical support
- Three years full warranty
Clients around the world, including the top universities, best medical schools, independent research centers, pharmaceutical and biotech companies.